Tuesday, September 2, 2008

Breast Cancer

Breast Cancer Death Rates Differ by Race

On whole, the report shows the continuation of a welcome trend -- a steady decrease each year in the rate of breast cancer deaths. Thanks to better methods of detecting cancers early and treatment advances, American women today are less likely to die of breast cancer than they have been in decades, said Harmon J. Eyre, MD, chief medical officer of the American Cancer Society.

Looking at the issue of race -- and the socioeconomic and genetic factors associated with race -- it becomes clear that this good news is better for some groups of women than for others. "Perhaps most troubling," said Eyre, "is the striking divergence in long-term mortality trends seen between African-American and white females that began in the early 1980s and that by 2004 had led to death rates being 36% higher in African-American women."

Other key statistics included in the report:

* An estimated 178,480 new cases of invasive breast cancer in women will be diagnosed in 2007, and approximately 40,460 deaths will be recorded. Only lung cancer accounts for more cancer deaths in women.

* In 2004 (the latest year for which figures are available), approximately 2.4 million women living in the US had a history of breast cancer. Breast cancer accounts for more than 1 in 4 cancers in US women.

* On average, the breast cancer death rate decreased by 2.2% each year between 1990 and 2004. Younger women saw an even more significant decline during that period.

* Breast cancer incidence among white women -- that is, the rate at which new breast cancers are diagnosed in this group -- fell by 3.7% a year during 2001-2004. Also declining during this time: the use of mammography and hormone replacement therapy (HRT) by white women. There was no significant change in breast cancer incidence among African-American women during this time, coinciding with stable mammography rates and HRT use.

* Among women 50 and older, incidence rates have been on a steep decline (by 4.8% per year) since 2001. Among women under age 50, incidence rates have remained stable since 1986.

* Since 2000, the incidence rate of smaller tumors has declined by 3.8% per year. In contrast, the incidence rate of larger tumors (>5.0 cm) has increased by 1.7% per year since 1992. (Larger tumor size at diagnosis is associated with decreased survival.) Both trends may be tied to an increase in obesity in postmenopausal women, HRT use, or both.

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